Is there any cream or some other medicine to reduce breast size?

No, there is not.

There are no creams or medicines that can reduce breast size. If the size of your breasts concerns you enough, I would suggest that you have a consultation with a plastic surgeon certified by the American Board of Plastic Surgery and ideally a member of the American Society for Aesthetic Plastic Surgery (ASAPS) that you trust and are comfortable with. You should discuss your concerns with that surgeon in person.

Robert Singer, MD FACS
La Jolla, California