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Multimodal Pilot Evaluation of a Hyaluronic Acid Infraorbital Filler Using Precise, Multipositional, 3-Dimensional Imaging Quantification, Patient-Reported Outcomes, and Anatomic Cadaveric Assessments

Aesthetic Surgery Journal Open Forum
Aesthetic Surgery Journal Open Forum

AUTHORS: Stephanie E Honig, MD, Yoshiko Toyoda, MD, Jane N Ewing, BS, Mehdi S Lemdani, BA, Zachary Gala, MD, Chris Amro, MD, Alexander T Wilson, MD, PhD, Robyn B Broach, PhD, Ivona Percec, MD, PhD

SUMMARY: In this study, 11 patients were injected with Volbella XC into the tear trough region and subsequently underwent undereye volumetric measurements over a 90-day period. Significant improvement was noted in the eyes, overall facial appearance, and cheekbones, irrespective of pretreatment severity. The authors also performed a cadaveric analysis in which Juvéderm Vycross and Restylane NASHA were injected into the infraorbital and malar region in 6 cephalus specimens. In the cadaver examination, the authors observed differences in the anatomic locations occupied by Juvéderm and Restylane products as well as in behavior after physical manipulation between gel types. The authors determined that Volbella XC effectively diminishes infraorbital hollowing as measured over a 90-day period. 

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